5-Amino-1MQ

other · endocrine · Oral

5-Amino-1MQ. Selective NNMT (nicotinamide N-methyltransferase) inhibitor — preserves cellular methyl donor (SAM) + NAD+ pools by preventing… Oral half-life 6 h.

Selective NNMT (nicotinamide N-methyltransferase) inhibitor — preserves cellular methyl donor (SAM) + NAD+ pools by preventing NAD-precursor sink. Mouse studies show fat-mass reduction + insulin sensitization. Research-chem availability outpaces clinical evidence.