Adamax
Adamax, a peptide. Sold as Semax (the ACTH(4-7) fragment Met-Glu-His-Phe with a C-terminal Pro-Gly-Pro) carrying an adamantane substituent, by analogy with P021 where…
Sold as Semax (the ACTH(4-7) fragment Met-Glu-His-Phe with a C-terminal Pro-Gly-Pro) carrying an adamantane substituent, by analogy with P021 where an adamantyl group was added to a neurotrophic peptide to improve brain penetration and resist exopeptidases. THAT DESCRIPTION IS A VENDOR CLAIM AND NOTHING MORE: no indexed paper describes an adamantane-modified Semax, so neither the structure nor any pharmacology attributed to it has a source. Semax itself is well published and is a separate record; anything read across from it is an assumption about a molecule whose identity is unverified.
NO mw_g_mol, DELIBERATELY. The parent Semax is PubChem CID 9811102 (C37H51N9O10S, 813.9) and its SMILES confirms Met-Glu-His-Phe-Pro-Gly-Pro, but the adamantane modification is uncorroborated by any indexed source, so there is no verifiable formula to take a mass from. Storing one — Semax's, or Semax plus an adamantyl increment — would give a vendor claim the appearance of a measurement, and mw_g_mol feeds real arithmetic elsewhere in this catalog. THE NINE ZERO-HIT SEARCHES, in full, so the next pass does not repeat them: adamantyl semax, adamantane semax, semax analog adamantane, Semax adamantyl derivative, Met-Glu-His-Phe-Pro-Gly-Pro adamantane, Pro-Gly-Pro adamantane, adamantylated peptide nootropic, ACTH(4-10) adamantane, adamantane ACTH fragment peptide — all zero, against 232 for `Semax`, 189 for `Semax derivatives` and 186 for `Semax analogues`, none of which overlap the adamantane set. NAMING TRAP, THE STRONGEST ON THIS LIST: all 39 PubMed hits for "Adamax" are the Adamax gradient-descent optimizer from machine learning (verified: PMID:42236259 "Adamax optimization for feature selection", PMID:42151246 "RMSPROP, and ADAMAX", PMID:41803168 "Adam, SGD, Adamax, AdamW, and Adadelta"), so any automated harvest on this token returns only ML papers and a citation-count heuristic would rate this the best-evidenced compound in the batch. WHY THE RECORD EXISTS AT ALL rather than being logged as a skip: the substance is sold and taken, and a catalog that omits it leaves a user who logs it with nothing, while a record that states plainly that no literature exists is itself the useful fact. The dose block is empty for the same reason it is empty on FOXO4-DRI — vendor label practice is not a studied regimen, and here there is not even a structure to anchor it to. Revisit if any indexed paper ever describes an adamantylated ACTH fragment.
Related compounds
- Semax — caution