Agmatine

metabolite · nervous · Oral

Agmatine, a metabolite. Decarboxylated arginine (arginine decarboxylase). Imidazoline I1/I2 receptor ligand; NMDA receptor antagonist at nitric-oxide site…

Decarboxylated arginine (arginine decarboxylase). Imidazoline I1/I2 receptor ligand; NMDA receptor antagonist at nitric-oxide site; α₂-adrenergic partial agonist. Proposed neuropathic-pain and mood-modulating effects, preclinical-dominant evidence.

Related compounds

• Arginine — synergistic

Sources: PMID:8786560, PMID:7715734, PMID:8930173, PMID:15982768, PMID:37770201, PMID:20447305