Alogliptin

pharmacological · cardiovascular · endocrine · renal · Oral

Alogliptin. DPP-4 inhibitor — same mechanism as sitagliptin, linagliptin, saxagliptin (raises endogenous GLP-1 + GIP). Renal dose adjustment needed. Heart failure…

DPP-4 inhibitor — same mechanism as sitagliptin, linagliptin, saxagliptin (raises endogenous GLP-1 + GIP). Renal dose adjustment needed. Heart failure signal in EXAMINE trial led to FDA boxed warning.

Sources: PMID:33952821, PMID:18538760, PMID:18405789