Articaine

pharmacological · nervous · musculoskeletal · Intramuscular · Subcutaneous

Articaine. Amide local anesthetic with thiophene ring + ester side group → rapid plasma esterase hydrolysis (lower systemic toxicity).… Intramuscular half-life 0.5 h.

Amide local anesthetic with thiophene ring + ester side group → rapid plasma esterase hydrolysis (lower systemic toxicity). Most-used dental local anesthetic in Europe + increasingly North America. Better diffusion through bone for mandibular blocks.