Atomoxetine

stimulant · nervous · Oral

Atomoxetine, a stimulant. Selective NET inhibitor — increases cortical NE + DA (NET co-clears DA in prefrontal cortex). No striatal DA effect → no… Oral half-life 5 h.

Selective NET inhibitor — increases cortical NE + DA (NET co-clears DA in prefrontal cortex). No striatal DA effect → no abuse liability (hence non-scheduled). Takes 4–6 weeks for full effect, unlike same-day stimulant response.

Pharmacokinetics

• Oral — t½ 5 h · F 63% · Vd 60 L

Sources: PMID:15910008, PMID:12431845