Beta-Carotene

vitamin · digestive · Oral

Beta-Carotene, a vitamin. Provitamin A: cleaved by BCMO1 in intestinal enterocytes into two retinal molecules, which are reduced to retinol.… Oral half-life 37 d.

Provitamin A: cleaved by BCMO1 in intestinal enterocytes into two retinal molecules, which are reduced to retinol. Conversion is regulated by vitamin A status — unlike preformed retinol, excess β-carotene does not accumulate as toxic retinoids. Also functions as a lipid-phase antioxidant and singlet-oxygen quencher.

Pharmacokinetics

• Oral — t½ 37.0 d · F 10%

Sources: PMID:27830502