β-Yohimbine

alkaloid · nervous · cardiovascular · Oral

β-Yohimbine, an alkaloid. A minor indole alkaloid of yohimbe bark (Pausinystalia johimbe) and a stereoisomer of yohimbine differing in configuration at the C-17…

A minor indole alkaloid of yohimbe bark (Pausinystalia johimbe) and a stereoisomer of yohimbine differing in configuration at the C-17 carbinol centre. Its own pharmacology is not characterised; by analogy to yohimbine it is presumed to interact with α-adrenoceptors, but this is not established for β-yohimbine specifically.

PubChem CID 3058605 (C21H26N2O3, MW 354.4; PubChem lists "amsonine"). Present in yohimbe bark: PMID:30059216 (alkaloids isolated from P. yohimbe bark).

Sources: PMID:30059216