Bufotenin

alkaloid · nervous · cardiovascular · Inhaled · IV · Intranasal

Bufotenin, an alkaloid. 5-hydroxy-DMT, a tryptamine found in Bufo toad venom and Anadenanthera seeds; a 5-HT2A / 5-HT1A agonist. Central psychoactivity is debated…

5-hydroxy-DMT, a tryptamine found in Bufo toad venom and Anadenanthera seeds; a 5-HT2A / 5-HT1A agonist. Central psychoactivity is debated (poor blood-brain-barrier penetration as the free base), while peripheral cardiovascular and autonomic effects are prominent.

PubChem CID 10257. 5-HT2A Ki deferred to enrichment pass.