Calcipotriene

topical · endocrine · integumentary · Transdermal

Calcipotriene, a topical compound. Topical vitamin D3 analog — VDR agonist on keratinocytes that normalizes hyperproliferation in… Transdermal half-life 14 h.

Topical vitamin D3 analog — VDR agonist on keratinocytes that normalizes hyperproliferation in psoriasis. Often combined with topical corticosteroid (calcipotriene + betamethasone, Taclonex) for synergistic plaque reduction.