Capsaicin (topical, high-strength)

topical · nervous · musculoskeletal · integumentary · Transdermal

Capsaicin (topical, high-strength), a topical compound. Topical TRPV1 agonist — chronic exposure desensitizes nociceptors → analgesia. OTC… Transdermal half-life 24 h.

Topical TRPV1 agonist — chronic exposure desensitizes nociceptors → analgesia. OTC at low strength for muscle/joint aches; Rx 8% patch (Qutenza) for post-herpetic neuralgia delivers extended relief from a single 60-min office application.