Cholestyramine

pharmacological · cardiovascular · digestive · Oral

Cholestyramine. Non-absorbed quaternary-ammonium resin that binds bile acids in the gut → prevents reabsorption → increases hepatic conversion of cholesterol → bile…

Non-absorbed quaternary-ammonium resin that binds bile acids in the gut → prevents reabsorption → increases hepatic conversion of cholesterol → bile acids → LDLR upregulation → LDL clearance. Older agent with poor tolerability.