Clobetasol Propionate

topical · endocrine · musculoskeletal · integumentary · Transdermal

Clobetasol Propionate, a topical compound. Super-high-potency topical glucocorticoid (Class I — most potent) — fluorinated + chlorinated… Transdermal half-life 6 h.

Super-high-potency topical glucocorticoid (Class I — most potent) — fluorinated + chlorinated steroid. Reserved for severe psoriasis, lichen planus, recalcitrant dermatitis. Two-week max courses on limited body areas to avoid HPA axis suppression and skin atrophy.