Clotrimazole

topical · digestive · reproductive · integumentary · immune-hematologic · Transdermal

Clotrimazole, a topical compound. Imidazole topical antifungal — fungal CYP51 (lanosterol 14α-demethylase) inhibitor blocking ergosterol… Transdermal half-life 4 h.

Imidazole topical antifungal — fungal CYP51 (lanosterol 14α-demethylase) inhibitor blocking ergosterol synthesis. OTC for tinea + cutaneous candidiasis + vaginal candidiasis. Minimal systemic absorption from topical route.