CMS121

pharmacological · nervous · Oral

CMS121. Investigational fisetin-derived small molecule studied in preclinical models of neurodegeneration. A phase 1 report describes oral administration in healthy…

Investigational fisetin-derived small molecule studied in preclinical models of neurodegeneration. A phase 1 report describes oral administration in healthy volunteers; that report is a preprint.

PK: PMID:40093210 is a preprint, not a peer-reviewed final paper. It reports substantial metabolite exposure and age-related PK variation; full source and analyte review remain open.

Sources: PMID:40093210, PMID:39422940