Colesevelam
Colesevelam. Same mechanism as cholestyramine but engineered polymer with higher bile-acid affinity + lower dose + better tolerability. Also lowers HbA1c in T2D…
Same mechanism as cholestyramine but engineered polymer with higher bile-acid affinity + lower dose + better tolerability. Also lowers HbA1c in T2D (independent indication — exact mechanism unclear, possibly via GLP-1 or bile-acid FXR signalling).