DHEA-Sulfate

hormone · endocrine · Oral

DHEA-Sulfate, a hormone. Sulfated DHEA — the dominant circulating form (DHEA-S:DHEA ratio ~300:1). Long half-life acts as a stable reservoir… Oral half-life 10 h.

Sulfated DHEA — the dominant circulating form (DHEA-S:DHEA ratio ~300:1). Long half-life acts as a stable reservoir; tissues desulfate locally via STS to access free DHEA → androstenedione → testosterone / estradiol.