Diphenoxylate / Atropine

pharmacological · nervous · Oral

Diphenoxylate / Atropine. Diphenoxylate (μ-opioid agonist with limited CNS access at therapeutic doses) + atropine (anticholinergic — added to deter abuse). Used for…

Diphenoxylate (μ-opioid agonist with limited CNS access at therapeutic doses) + atropine (anticholinergic — added to deter abuse). Used for symptomatic diarrhea. Schedule V due to abuse-potential precedent; loperamide largely supplanted it.

Sources: PMID:3682841