Enzalutamide
Enzalutamide. Androgen receptor antagonist — blocks AR ligand binding, AR nuclear translocation, and AR-DNA binding. Stronger than first-generation bicalutamide.…
Androgen receptor antagonist — blocks AR ligand binding, AR nuclear translocation, and AR-DNA binding. Stronger than first-generation bicalutamide. Castration-resistant prostate cancer. Strong CYP3A4 inducer (auto-induces own clearance + lowers many co-medications).
Sources: PMID:30642613, PMID:19359544, PMID:25917876