EPA

lipid · cardiovascular · immune-hematologic · Oral

EPA, a lipid. C20:5 ω-3 polyunsaturated fatty acid. Substrate for COX/LOX enzymes generating series-3 (less inflammatory) prostaglandins +… Oral half-life 18 h.

C20:5 ω-3 polyunsaturated fatty acid. Substrate for COX/LOX enzymes generating series-3 (less inflammatory) prostaglandins + thromboxanes + series-5 leukotrienes. Direct modulator of inflammatory gene expression via PPAR-α, FFAR4. Cardiovascular + triglyceride-lowering effects.