Omega-3 (EPA/DHA)
Omega-3 (EPA/DHA), a lipid. Long-chain ω-3 PUFAs. Incorporate into phospholipid membranes → altered fluidity + eicosanoid precursor shift away from arachidonic acid.…
Long-chain ω-3 PUFAs. Incorporate into phospholipid membranes → altered fluidity + eicosanoid precursor shift away from arachidonic acid. EPA → resolvins E-series; DHA → protectins + resolvins D-series (pro-resolution lipid mediators). REDUCE-IT trial 2019 demonstrated CV event reduction with 4 g/day EPA ethyl ester; mixed-EPA-DHA trials have been less consistently positive.
Related compounds
- Arachidonic Acid — caution
- Docosapentaenoic Acid (n-3) — synergistic
Sources: PMID:30415628, PMID:22332096