GHK-Cu

peptide · integumentary · Transdermal · Subcutaneous · Intranasal

GHK-Cu, a peptide. Tripeptide Gly-His-Lys chelates Cu²⁺ to form a stable planar complex. Binds LOXL2 + SPARC → collagen + elastin gene upregulation. Also activates…

Tripeptide Gly-His-Lys chelates Cu²⁺ to form a stable planar complex. Binds LOXL2 + SPARC → collagen + elastin gene upregulation. Also activates wound-healing mediators (MMP-2, VEGF, FGF-2). Hair-growth claims derive from dermal-papilla stimulation. Declines ~70% from ages 20 → 60 in plasma.