Glycine
Glycine, an amino acid. Inhibitory neurotransmitter; lowers core body temp via cutaneous vasodilation. Oral half-life 1 h.
Inhibitory neurotransmitter; lowers core body temp via cutaneous vasodilation.
F 0.9 REMOVED as an R6 stored default, and the cited design forbids the value outright: PMID:8212419 administered glycine by INTRAVENOUS INFUSION, so it cannot state an oral bioavailability. Its headline finding is that glycine kinetics are non-linear — "The apparent half-life of glycine varied 10-fold (range 26-245 min) and increased in direct proportion to the amount of glycine given" — which a dose-independent F contradicts rather than rests on. Numerically a no-op against the 0.9 default.
Pharmacokinetics
- Oral — t½ 1 h · Vd 25 L
Related compounds
- NAC — synergistic
Sources: PMID:12450897