Low-Molecular-Weight Hyaluronic Acid

topical · integumentary · immune-hematologic · Transdermal

Low-Molecular-Weight Hyaluronic Acid, a topical compound. Smaller HA fragments penetrate the stratum corneum (vs HMW which stays on the surface). In dermis, fragments…

Smaller HA fragments penetrate the stratum corneum (vs HMW which stays on the surface). In dermis, fragments can trigger inflammatory signalling via TLR2/4 — context-dependent pro-inflammatory or regenerative. Current cosmetic positioning: deeper hydration than HMW forms alone.