Icariin

flavonoid · reproductive · musculoskeletal · Oral

Icariin, a flavonoid. Prenylated flavonoid from Epimedium species. Weak PDE5 inhibition + estrogenic activity; mechanistic basis for the… Oral half-life 3 h.

Prenylated flavonoid from Epimedium species. Weak PDE5 inhibition + estrogenic activity; mechanistic basis for the traditional erectile / libido + osteoporosis indications. Bioavailability poor; deglycosylated icaritin has higher absorption.