Idebenone
Idebenone, a nootropic. Synthetic CoQ10 analog — short benzoquinone tail enables better mitochondrial penetration vs CoQ10. Bypasses defective… Oral half-life 18 h.
Synthetic CoQ10 analog — short benzoquinone tail enables better mitochondrial penetration vs CoQ10. Bypasses defective Complex I in Leber's hereditary optic neuropathy (FDA-approved for LHON in EU); marketed off-label for cognitive support.