Insulin Glargine

pharmacological · endocrine · Subcutaneous

Insulin Glargine. Long-acting basal insulin analog — A21Asn→Gly + B-chain Arg-Arg extension shifts pI to ~7, producing slow precipitation in subcutaneous tissue →…

Long-acting basal insulin analog — A21Asn→Gly + B-chain Arg-Arg extension shifts pI to ~7, producing slow precipitation in subcutaneous tissue → flat 24h profile. Once-daily SC for T1D + T2D basal coverage.

Sources: PMID:26086190