Luteolin

flavonoid · immune-hematologic · Oral

Luteolin, a flavonoid. Flavone with strong mast-cell-stabilising activity and microglial anti-inflammation (blocks IFN-γ-induced microglial… Oral half-life 3 h.

Flavone with strong mast-cell-stabilising activity and microglial anti-inflammation (blocks IFN-γ-induced microglial activation). PDE4 inhibition contributes to anti-inflammatory profile. Attenuates oxidative stress via Nrf2 pathway.

Pharmacokinetics

• Oral — t½ 3 h · F 26% · Vd 84 L

Sources: PMID:15113710