MCT C8

lipid · cardiovascular · immune-hematologic · Oral

MCT C8, a lipid. C8 (caprylic acid) triglyceride — the most ketogenic MCT. Absorbed via portal vein (vs lymphatic transport of long-chain FAs)… Oral half-life 2 h.

C8 (caprylic acid) triglyceride — the most ketogenic MCT. Absorbed via portal vein (vs lymphatic transport of long-chain FAs), bypasses chylomicron formation, and directly reaches liver where β-oxidation produces acetyl-CoA faster than the TCA cycle can consume it → ketogenesis. Raises plasma BHB ~0.3–0.5 mmol/L within 60–90 min — milder than ester-based products but sustained over 3–4 h.

Pharmacokinetics

• Oral — t½ 2 h · F 95%

Related compounds

• MCT C10 — synergistic

Sources: PMID:31058159