Melanotan II

peptide · endocrine · digestive · integumentary · immune-hematologic · Subcutaneous

Melanotan II, a peptide. Non-selective MCR agonist: activates MC1R (melanocortin-1, melanogenesis → tanning), MC3R + MC4R (satiety, energy expenditure), and MC5R…

Non-selective MCR agonist: activates MC1R (melanocortin-1, melanogenesis → tanning), MC3R + MC4R (satiety, energy expenditure), and MC5R (sebum / immune). The MC4R-mediated effects drive appetite suppression and the sexual-response effects that led to the related PT-141 (bremelanotide) development. Unregulated product contamination is common; associated with spontaneous-priapism case reports.

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