Menthol

terpenoid · nervous · Oral · Transdermal · Inhaled

Menthol, a terpenoid. Cyclic monoterpene from Mentha species. Activates TRPM8 cold-receptor channels → cooling sensation; also weak Ca²⁺-channel… Oral half-life 1.5 h.

Cyclic monoterpene from Mentha species. Activates TRPM8 cold-receptor channels → cooling sensation; also weak Ca²⁺-channel modulation. Topical analgesic, decongestant, GI antispasmodic.