Nitrofurantoin

pharmacological · respiratory · digestive · immune-hematologic · Oral

Nitrofurantoin. Nitrofuran antibiotic — bacteria reduce the nitro group to reactive radicals that damage DNA + ribosomes. Concentrates in urine; used almost…

Nitrofuran antibiotic — bacteria reduce the nitro group to reactive radicals that damage DNA + ribosomes. Concentrates in urine; used almost exclusively for uncomplicated UTIs. Pulmonary fibrosis + hepatotoxicity at chronic suppressive use.

Sources: PMID:30859184, PMID:18429968, PMID:30184207