Nitrous Oxide

pharmacological · nervous · immune-hematologic · Inhaled

Nitrous Oxide. Inhaled anesthetic gas; an NMDA-receptor antagonist with additional opioid and GABA-A modulation, producing brief euphoria, analgesia, and dissociation…

Inhaled anesthetic gas; an NMDA-receptor antagonist with additional opioid and GABA-A modulation, producing brief euphoria, analgesia, and dissociation ("whippets"). Chronic use inactivates vitamin B12 (oxidizes its cobalt core), causing functional B12 deficiency and subacute combined degeneration / neuropathy.

PubChem CID 948. Dose ≈ standard 8 g charger.