Nooglutyl

pharmacological · nervous · Oral

Nooglutyl. Investigational N-hydroxynicotinoyl glutamate studied in animal models of neurological injury. Noogutyl is treated here as a spelling variant of nooglutyl…

Investigational N-hydroxynicotinoyl glutamate studied in animal models of neurological injury. Noogutyl is treated here as a spelling variant of nooglutyl and should be checked against the product identity.

ROUTE: Oral formulation research included rabbits. PRODUCT IDENTITY: Noogutyl was inferred to refer to nooglutyl; verify the product label and chemical identity. Calcium salt and free acid are not automatically interchangeable. MASS: PubChem CID 147523, free compound, molecular weight 268.22 g/mol; salt forms may differ. PK: PMID:21395015 studied the calcium salt after bolus dosing in rats and rabbits, with different half-lives and a two-compartment profile. Its human half-life was an allometric prediction, not a measurement; it is not used here.

Sources: PMID:8704601, PMID:9783110, PMID:21395015