NSI-189

nootropic · nervous · Oral

NSI-189, a nootropic. Hippocampal neurogenesis stimulator — exact mechanism partially defined; raises BDNF + ERK1/2 + dentate gyrus neurogenesis… Oral half-life 17 h.

Hippocampal neurogenesis stimulator — exact mechanism partially defined; raises BDNF + ERK1/2 + dentate gyrus neurogenesis in animal studies. Failed Phase 2 for major depressive disorder in 2017; biohacker interest persists.