Oxandrolone

hormone · endocrine · digestive · Oral

Oxandrolone, a hormone. Dihydrotestosterone derivative with 2-oxa substitution + 17α-methyl group (oral bioavailability). Anabolic:androgenic… Oral half-life 10 h.

Dihydrotestosterone derivative with 2-oxa substitution + 17α-methyl group (oral bioavailability). Anabolic:androgenic ratio ~3–24:1 in rodent assays. Does not aromatise — no estrogen-related gyno / water retention. Hepatotoxicity from 17α-alkylation is the main dose limiter.

Pharmacokinetics

• Oral — t½ 10.4 h

Sources: PMID:32265605