Polydeoxyribonucleotide

biologic · integumentary · cardiovascular · Intramuscular

Polydeoxyribonucleotide, a biologic. DNA-fragment preparation investigated for tissue repair and angiogenesis, with adenosine A2A receptor-related effects reported in…

DNA-fragment preparation investigated for tissue repair and angiogenesis, with adenosine A2A receptor-related effects reported in wound-healing research. It is a distribution of nucleotide polymers rather than a single defined small molecule.

IDENTITY: PMID:33033366 describes salmon-sperm-derived DNA material; source and fragment distribution are preparation-specific. ROUTE: The corrected abstract of PMID:24483158 reports IM and perilesional administration over eight weeks for diabetic foot ulcers. IM is represented here; perilesional injection has no dedicated route code and is not automatically labeled SC. A ProPDRN cream is a finished formulation, not an alias for this ingredient, and injectable study results do not establish topical bioavailability. DOSE: PMID:29076318 reports 5.625 mg in 3 mL per injection, IM five days per week and perilesional two days per week for two weeks in a small diabetic-foot-ulcer trial. Its full-text Experimental protocol identifies Rejuvenex and intradermal perilesional injection. This preparation-specific research regimen is not a generic dose default.

Sources: PMID:24483158, PMID:25658154, PMID:29076318, PMID:33033366