Retinol
Retinol, a vitamin. Retinol is oxidised to retinal (11-cis-retinal in rhodopsin → vision) and further to retinoic acid, which binds RAR/RXR nuclear receptors and…
Retinol is oxidised to retinal (11-cis-retinal in rhodopsin → vision) and further to retinoic acid, which binds RAR/RXR nuclear receptors and regulates >500 genes controlling epithelial differentiation, immune function, and embryonic development. Stored in liver as retinyl esters; preformed vitamin A accumulates (unlike β-carotene where conversion is regulated).
Related compounds
- Isotretinoin — contraindicated
Sources: PMID:27830502, PMID:3294938