Sodium Fluoride

topical · integumentary · Transdermal · Oral

Sodium Fluoride, a topical compound. Topical / dietary fluoride source — incorporates into hydroxyapatite as fluorapatite, hardening enamel… Transdermal half-life 4 h.

Topical / dietary fluoride source — incorporates into hydroxyapatite as fluorapatite, hardening enamel and resisting demineralization. Toothpaste at 1000–1500 ppm; prescription 5000 ppm for high-caries patients; community water fluoridation at 0.7 ppm.