Sofosbuvir

pharmacological · immune-hematologic · Oral

Sofosbuvir. HCV NS5B nucleotide polymerase inhibitor — uridine analog phosphorylated to active triphosphate, a chain-terminator for HCV RNA polymerase. Backbone of…

HCV NS5B nucleotide polymerase inhibitor — uridine analog phosphorylated to active triphosphate, a chain-terminator for HCV RNA polymerase. Backbone of pan-genotypic HCV cure regimens (typically combined with NS5A inhibitor).

Sources: PMID:32053101, PMID:25822283