Succinylcholine
Succinylcholine. Depolarizing neuromuscular blocker — sustained nicotinic ACh receptor activation → fasciculations → flaccid paralysis. Fastest… IV half-life 0.1 h.
Depolarizing neuromuscular blocker — sustained nicotinic ACh receptor activation → fasciculations → flaccid paralysis. Fastest onset of any NMB (~30 sec). Hyperkalemia risk in burns, denervation, prolonged immobility. Trigger for malignant hyperthermia.
DOSE CORRECTED FROM A PER-KILOGRAM VALUE STORED AS AN ABSOLUTE ONE. The IV block read {"min":1,"max":2,"typical":1.5,"unit":"mg"} — those are mg/kg, not mg, and `doses` admits only absolute mg/g/mcg/IU, so occupancy was being judged at about a seventieth of a real dose. Label verbatim: "The average dose required to produce neuromuscular blockade and to facilitate tracheal intubation is 0.6 mg/kg ANECTINE given intravenously". At the 70 kg reference that is 21-77 mg, typical 42 mg — ARITHMETIC, mg/kg x 70 kg. Source: Anectine (succinylcholine chloride) injection, DailyMed set id 04a4e6f5-6fa1-42e1-a3f9-21fca7786b15, v9 published 2026-08-03. THE LABEL SUPPLIES ALL THREE FIGURES: 0.6 mg/kg is its own stated average, and the next sentence gives the spread — "The optimum intravenous dose will vary among patients and may be from 0.3 to 1.1 mg/kg for adults". FOUND BY `occupancy.ts`: nothing reading one field at a time can see this, because every number in the row is individually well-formed.
Sources: PMID:16571968, PMID:15169739