Syn-AKE active peptide
Syn-AKE active peptide, a peptide. Synthetic cosmetic peptide studied with computational docking and molecular-dynamics methods against MMPs and SIRT1, alongside…
Synthetic cosmetic peptide studied with computational docking and molecular-dynamics methods against MMPs and SIRT1, alongside in-vitro antioxidant, cytotoxicity and genotoxicity assays. These findings do not establish clinical anti-aging efficacy or a human systemic mechanism.
EVIDENCE: PMID:37349941 studies Syn-Ake using computational and laboratory assays, not human pharmacokinetics or an isolated-ingredient clinical efficacy trial. ROUTE: TD is retained as a cosmetic presentation category; the cited assays do not establish skin penetration or systemic delivery. No human dose, receptor-affinity parameter or elimination half-life is assigned.
Sources: PMID:37349941