Tranexamic Acid (topical)

topical · integumentary · Transdermal · Oral

Tranexamic Acid (topical), a topical compound. Synthetic lysine analog — competitively inhibits plasminogen binding to lysine residues → blocks plasmin activation.…

Synthetic lysine analog — competitively inhibits plasminogen binding to lysine residues → blocks plasmin activation. Anti-fibrinolytic (approved in menorrhagia, trauma bleeding). Topical/oral melasma effect proposed via inhibition of plasmin-mediated keratinocyte-driven melanocyte stimulation.