Valerenic acid

terpenoid · nervous · Oral

Valerenic acid, a terpenoid. Sesquiterpenoid; positive allosteric modulator at GABA-A β3 subunit. Primary anxiolytic + sleep-promoting bioactive… Oral half-life 1.1 h.

Sesquiterpenoid; positive allosteric modulator at GABA-A β3 subunit. Primary anxiolytic + sleep-promoting bioactive in Valeriana officinalis root extracts. Standardized supplements often target ≥0.8% valerenic acid as a marker.