Calcium / phosphate / PTH / vitamin D axis

endocrine_axis · endocrine · musculoskeletal · renal

Calcium / phosphate / PTH / vitamin D axis. Endocrine axis pathway. Coupled homeostatic loop. Plasma Ca2+ low → parathyroid CaSR senses → PTH released → (1) bone…

Modulators

• cholecalciferol — substrate
• cinacalcet — activator

Sources: PMID:17634462, PMID:30060226