Cardiac action potential

membrane · cardiovascular

Cardiac action potential. ion channels + antiarrhythmic targets. Membrane pathway. Ventricular AP has 5 phases. Phase 0 (rapid depolarization): voltage-gated Na+…

Modulators

• quinidine — inhibitor
• mexiletine — inhibitor
• flecainide — inhibitor
• propafenone — inhibitor
• amiodarone — inhibitor
• sotalol — inhibitor
• dofetilide — inhibitor
• ivabradine — inhibitor
• lidocaine — inhibitor
• digoxin — inhibitor

Sources: PMID:16183911