cGAS-STING cytosolic DNA sensing → type I IFN

immune_innate · immune-hematologic · integumentary

cGAS-STING cytosolic DNA sensing → type I IFN. Innate immunity pathway. cGAS-STING is the cytosolic dsDNA sensor that triggers type I interferon (IFN-α/β) — central…

Modulators

• hydroxychloroquine — inhibitor
• tofacitinib — inhibitor
• baricitinib — inhibitor
• ruxolitinib — inhibitor
• upadacitinib — inhibitor
• rapamycin — inhibitor
• dexamethasone — inhibitor
• colchicine — inhibitor
• colchicine-low-dose-cv — inhibitor
• metformin — inhibitor

Sources: PMID:32668227, PMID:25517616