Coagulation cascade

biosynthesis · immune-hematologic · cardiovascular

Coagulation cascade. extrinsic + intrinsic → common. Biosynthesis pathway. Sequential serine-protease activations producing thrombin (factor IIa) and ultimately…

Modulators

• warfarin — inhibitor
• apixaban — inhibitor
• rivaroxaban — inhibitor
• edoxaban — inhibitor
• dabigatran — inhibitor
• heparin — inhibitor
• enoxaparin — inhibitor

Sources: PMID:18753650, PMID:21870978