Cytokine pathway biologic blockade

immune_innate · immune-hematologic · integumentary

Cytokine pathway biologic blockade. TNF / IL-17 / IL-23 / IL-4-13 / IgE. Innate immunity pathway. Therapeutic mAbs + fusion proteins target inflammatory cytokines +…

Modulators

• etanercept — inhibitor
• certolizumab-pegol — inhibitor
• golimumab — inhibitor
• secukinumab — inhibitor
• ixekizumab — inhibitor
• ustekinumab — inhibitor
• guselkumab — inhibitor
• risankizumab — inhibitor
• dupilumab — inhibitor
• omalizumab — inhibitor

Sources: PMID:28612747