Hypothalamic-pituitary-thyroid axis

endocrine_axis · endocrine

Hypothalamic-pituitary-thyroid axis. Endocrine axis pathway. Thyroid hormone homeostasis loop. Hypothalamic TRH → anterior pituitary TSH → thyroid follicle cells → T4…

Modulators

• levothyroxine — substrate
• methimazole — inhibitor
• amiodarone — inhibitor
• liothyronine — activator
• propylthiouracil — inhibitor

Sources: PMID:22945636